A study showed Mast Cell Activation Syndrome patients had higher rates in all but 1-2 of 19 neurological disorders studied.
Among 14 psychiatric disorders additionally studied, female MCAS patients reported higher rates in all and male MCAS patients reported higher rates in 8 disorders.
“MCAS subjects have significantly elevated odds ratios for many neuropsychiatric disorders and may see improvement of symptoms using MCAS-targeted therapies, suggesting that mast cell dysregulation affects the brain and peripheral nervous systems and contributes to neuropsychiatric symptoms.”